Agilent TRS100 Raman quantitative pharmaceutical analysis system
Eliminate sample preparation and reduce QC testing by days—or weeks—with transmission Raman spectroscopy (TRS).
TRS is ideal for quantitative measurements of oral solid dose forms, such as tablets and capsules. The technique complements HPLC, UV-Vis, and other traditional analytical techniques for content uniformity (CU) testing, and offers these advantages:
Anders Sparén, associate principal scientist at AstraZeneca, talks about how TRS can be used to improve analytical workflows and operational efficiencies. In this webinar, you will:
The Agilent TRS100 has features that facilitate working in compliant environments. It is ideal for labs that must comply with US FDA 21 CFR Part 11, as well as USP and EP chapters for Raman spectroscopy.
Pharmaceutical manufacturing facilities have also found that switching from standard methods to TRS has:
The Agilent TRS100 has been recognized by the independent third party My Green Lab for its sustainable attributes and has been assigned an accountability, consistency, and transparency (ACT) label based on its environmental impact.
Learn moreRaman spectroscopy, a vibrational spectroscopic technique, provides a chemical fingerprint of the compounds being analyzed. The spectra produced have sharp, distinctive peaks that correspond to molecular vibrations of the chemical functional groups.
TRS is a measurement that scatters light through a material, and is well suited for pharmaceutical tablets and capsules. The laser is on the opposite side of the sample to the detector, resulting in the Raman signal being collected from the bulk of the material. In pharmaceutical products, each ingredient can have many Raman peaks that combine in number and intensity to provide the spectrum.
Adding Transmission Raman spectroscopy as a complimentary content uniformity (CU) analytical method could make a big difference in your bottom line.
To see how your savings can add up, input the key variables of your existing CU analytical workflows into this quick calculator tool.
Input your variables | Input | |
---|---|---|
batches | ||
hours | ||
mL | ||
minutes |
Compare the results | Traditional analysis | TRS | |
---|---|---|---|
Cost per batch | 869 | $55 | |
Total workflow time | 6.5 hrs | 1 hr | |
Total solvent used | 8 | 0 L | |
Cost per sample | 87 | $5 |
TRS provides a fast, nondestructive bulk analysis of tablets and capsules. This regulatory-approved technique negates the need for sample preparation, saving you time, solvents, and consumables.
Save 750 operator hours per year that could be used elsewhere.
5,000 saved per year.
Save 1,900 L of solvent per year by eliminating sample preparation, clean up, and disposal.
61,000 saved per year.
17 times faster than traditional analysis.
333 hours saved per year.
When multiple analytical methods are deployed, your cost savings and return on investment increase dramatically.
The calculations shown on this page are illustrative estimations using industry standard values verified with existing system users. To work through a customized calculation with your local Transmission Raman product specialist, contact us.
Request a custom calculationWhat are the advantages of Raman spectroscopy? How does Raman spectroscopy compare with other traditional techniques? What technologies should your lab focus on in the face of ever-tightening budgets?
You’ll learn the answers to these and other questions in our new webinar, featuring a panel of thought leaders from the pharmaceutical industry.