Gastric cancer remains a complex and heterogeneous disease, demanding a multidisciplinary approach to optimize patient outcomes. This on-demand talk explores the pivotal role of pathology in the multidisciplinary management of gastric cancer. Through real-world patient cases, it demonstrates how the interpretation of key biomarkers, including HER2, PD-L1, MMR, and others, directly informs therapeutic decisions in line with evolving clinical guidelines. The presentation is structured around three core perspectives: clinical, diagnostic, and quality (EQA). We emphasize the responsibility of the pathologist not only in accurate biomarker assessment but also in ensuring diagnostic consistency and quality that underpin effective treatment planning. As precision oncology advances, the pathologist becomes a central figure in translating molecular insights into actionable clinical strategies in gastric cancer.
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MD, PhD, Head of Pathology Department at Fundación Jiménez Díaz

Scheme Director of UK NEQAS for Immunocytochemistry and In-Situ Hybridisation

MD, PhD, Medical Oncology Department, Hospital Clínico Universitario de Valencia-INCLIVA
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