Agilent SurePrint microarray success stories

Gene expression arrays can provide better results with respect to RNA sequencing (RNA-Seq) for gene expression profiling. A study comparing the performance of Agilent microarray versus RNA-Seq platforms demonstrated that both methods provided similar technical ability in gene expression analysis. However, microarrays showed better sensitivity for detection of low-expressed genes.

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The Oxford Biodynamics EpiSwitch Explorer Array Kit has enabled researchers to explore 3D genomic biomarker discovery at high resolution, and is compatible with Agilent SureScan microarray scanners. See how this custom microarray allows simultaneous interrogation of over 960,000 high-confidence chromosome conformations across the human genome.

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Circular RNAs (circRNAs) are usually present at much lower levels compared to linear RNA, making its expression profiling difficult using technologies such as RNA-Seq. Microarray accuracy remains relatively unchanged despite lower transcript levels and are an ideal solution. Arraystar Circular RNA Arrays enable systematic profiling of highly sensitive and specific circRNA expression levels from sample to data.

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High-throughput microarray technology has significantly improved ecological monitoring by enabling high sensitivity detection in complex environmental samples, supporting pathogen discrimination. Magigene’s Cyanochip precisely identifies and quantifies cyanobacteria strains using two-color fluorescent labeling, supporting the prediction of toxic algal blooms by monitoring community changes.

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This study highlights the use of microarray technology to analyze genome-wide chromatin accessibility patterns, termed Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq). See how ATAC-seq microarray technology can enable complex analysis with an easier workflow, simplified data analysis, and lower cost without compromising data quality in cancer research.

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Microarray hybridization-based detection offers rapid and sensitive analysis of molecules, even in highly complex samples. Agilent microarrays can be customized to target any genomic sequence, as demonstrated by the creation of the Agilent Pathochip. This innovative community-designed pathogen research microarray can detect and identify thousands of different pathogens in a single assay.

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Gene expression arrays can provide better results with respect to RNA sequencing (RNA-Seq) for gene expression profiling. A study comparing the performance of Agilent microarray versus RNA-Seq platforms demonstrated that both methods provided similar technical ability in gene expression analysis. However, microarrays showed better sensitivity for detection of low-expressed genes.

See full study