The New Gold Standard for GC/MS: Agilent J&W DB 5Q and HP-5Q GC Columns

Get the most from your MS

As mass spectrometry continues to push the boundaries of sensitivity and speed, you need a column that can do the same. Agilent J&W 5Q GC columns ensure optimal analyte delivery to your quadrupoles, so you can stretch your science to the limit.

Ultra low-bleed performance enhances data accuracy with high spectral fidelity and stable baseline integration.
Ultra inert performance increases sensitivity for active, trace-level analytes and provides balanced deactivation for multiclass analyte panels.
Ultrafast conditioning and outstanding column durability improve uptime by minimizing the frequency of column changes.
Compatibility with any GC/MS system ensures a seamless fit for all Agilent GC platforms.

These innovative columns are available in conventional, high-efficiency, hydrogen-compatible, and backflushing dimensions.

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How can the right GC column improve your data quality?

In today’s data driven and competitive environment, highest data quality is paramount. High data quality leads to better business outcomes, ensures regulatory compliance and aids in minimizing costly re-runs. 5Q columns were designed to optimize GC/MS⁠—improved sensitivity, optimal peak shape, and enhanced spectral accuracy⁠—and provide the utmost confidence in your trace-level of analyses. Here’s how:

Improved sensitivity

Agilent J&W 5Q GC columns have significantly lower bleed profiles, resulting in more stable baselines. This ensures accurate integration, especially for trace-level analytes with low signal-to-noise ratios. Explore our Ultra Low-Bleed columns.

Optimized peak shape

A noninert GC column can cause peak tailing, resulting in signal loss and less accurate peak integrations. Agilent J&W 5Q GC columns feature industry-leading ultra inert deactivation chemistry that was designed to improve peak shape for problematic, active analytes. Agilent J&W 5Q columns let you confidently quantify low-level, active compounds. Explore our Ultra Low-Bleed columns.

Enhanced spectral accuracy

Agilent J&W 5Q Ultra Low-Bleed columns deliver enhanced spectral accuracy, when compared to conventional 5ms phase columns. By significantly reducing interfering bleed ions, 5Q columns provide higher spectral accuracy for improved analyte identification and confidence. Explore our Ultra Low-Bleed columns.

Extended durability

Agilent J&W 5Q columns deliver extended durability when compared to conventional 5ms phase columns. Chromatographic performance can degrade quickly for problematic analytes resulting in costly column exchanges. Agilent J&W 5Q columns extend the need for column exchanges and provide consistent retention times and peak shapes run after run. Explore our Ultra Low-Bleed columns.

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Increasing confidence during reporting

“The new 5Q columns were essentially a plug and play update to our aging HP 5MS UI columns. We have noticed a decrease in the amount of noise/bleed from the columns themselves during the high ramp temperature regions of our analytical pesticide method. This has allowed us to add additional analytes to our method for orthogonal analysis between LC and GC techniques and therefore increasing our confidence during reporting. We are very satisfied with the column’s performance in regard to retention time shifting, overall bleed reduction, and reproducibility.”

Phillip Lynch
Lead Chemist, US Cannalytics

Reduce detection limits, accelerate throughput, and improve the quality of your results

Raising the bar on MS column reliability and productivity

By combining ultra inert surface deactivation with ultra low-bleed polymer chemistry, HP-5Q columns deliver exceptional peak symmetry and signal-to-noise ratios. They’re ideal for challenging analytes, such as pesticides, dioxins, PCBs, and other semivolatiles.

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Beyond all limits: Agilent 7010D GC/TQ

Push all boundaries for ultratrace analysis. The robust 7010D GC/TQ features a high-efficiency source (HES) 2.0 that provides attogram-level sensitivity, while heated gold quadrupoles and JetClean ion source deliver unmatched performance and reliability.

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Make Agilent your one-stop source for GC/MS columns and supplies

Agilent Ultra inert inlet liners and HydroInert source

Ensure inertness from injection through detection

Agilent Inert Flow Path solutions minimize activity along every step of your GC and GC/MS flow path, improving your results and minimizing unplanned maintenance.

Extend column life and control column bleed

Agilent self tightening column nuts deliver a finger-tight connection and maintain a leak-free seal even after hundreds of injections.

Maintain peak GC/MS performance

All Agilent GC columns, supplies, and accessories are designed and optimized for Agilent GC instruments and meet the industry’s tightest quality control specifications.

Put 50 years of quality and innovation behind your GC separations

2024 marks the 50th anniversary of Agilent J&W GC columns. Throughout these five decades, our industry-first innovations have set the foundation for the GC columns we know today. As you strive to maximize the productivity and performance of your GC instrumentation, you can count on Agilent J&W GC columns.

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The New Gold Standard for GC/MS