Configure Your 2D-LC

Agilent ranks #1 in 2D-LC

Agilent InfinityLab 2D-LC Solutions achieve best results in all categories.

In an average of all categories, Agilent ranked far ahead of other vendors.

Since 2016, Agilent has consistently been the market leader in 2D-LC—with increasingly positive results.

With 10 years of experience in 2D-LC, Agilent has fine-tuned their workflow, establishing InfinityLab 2D-LC Solutions as the clear market leader year-after-year. Our complete 2D-LC solutions are fully customizable using Agilent’s proven modular LC systems.

See why our customers are saying that an Agilent 2D-LC solution is the preferred choice for their business. Configure the perfect 2D-LC solution for your application and budget—try our product selector now.

Configure your 2D-LC

Please answer all six questions below. Then click “Show result” to find your recommended Agilent InfinityLab 2D-LC Solution and discover attractive offers just for you.

1. What is your primary goal for using 2D-LC?

2. What is your preferred mode of detection?

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Increase resolution for one peak

Increase resolution for multiple peaks

Increase resolution for one or multiple broad peaks

Analyze my complete sample using two different chromatographic conditions

Make buffer-based separations MS-compatible, avoid offline fractionation, or automate sample preparation

Select your answer

UV or MSD detection

Triple quadrupole (TQ) detection

Quadrupole time-of-flight (Q-TOF) detection

3. Do you use samples that are sensitive to stainless steel surfaces, or do you have to work with harsh solvent conditions?

4. Are you interested in the analysis of monoclonal antibodies?

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Yes

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Yes

5. Do you want to use 2D-LC for quality control of your samples?

6. Already have an Agilent 1290 Infinity II LC or 1290 Infinity II Bio LC that you are interested in upgrading to a 2D-LC?

Select your answer

Yes

Select your answer

Yes

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Configure your 2D-LC

Your recommendation:

Agilent InfinityLab 2D-LC Solution

Agilent 1290 Infinity II 2D-LC System

Agilent 2D-LC Software for OpenLab CDS

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For your application, we recommend the Agilent 1290 Infinity II 2D-LC System with a 2D-LC Valve. This system is well-suited for single heart-cutting for orthogonal separations and comprehensive 2D-LC for highly complex samples.

Adding Multiple Heart-Cutting Valves to this system would strongly increase the flexibility for method setup and development to achieve optimal resolution, even for multiple peaks in the first-dimension chromatogram.

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Direct Analysis of In-Process Oligonucleotides Without Manual Purification

Use Agilent 2D-LC Software for OpenLab CDS to easily set up and develop methods, as well as analyze and report results for UV or single quadrupole (MSD) detection. It fully supports qualitative and quantitative workflows.

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Direct Analysis of In-Process Oligonucleotides Without Manual Purification

Take advantage of the biocompatible 2D-LC system with MP35N and other noble materials. This system is optimal for demanding solvent and sample conditions over a wide pH range and for high-salt concentrations, as well as for minimal sample interaction with the flow path surface. Active Solvent Modulation is included for maximum flexibility in solvent choice, highest resolution, and sensitivity.

Consider choosing a biocompatible 2D-LC system with MP35N and other noble materials. This system is optimal for demanding solvent and sample conditions over a wide pH range and for high-salt concentrations, as well as for minimal sample interaction with the flow path surface.

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Direct Analysis of In-Process Oligonucleotides Without Manual Purification

Facilitate your monoclonal antibody (mAb) analysis with the Agilent InfinityLab 2D-LC ProtA-SEC Kit, which allows automated titer and aggregation analysis of mAbs in high reproducibility with your 2D-LC system. Save 80% of time and eliminate issues with manual handling or potential antibody degradation. This kit is optionally available with a service for workflow implementation.

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Direct Analysis of In-Process Oligonucleotides Without Manual Purification

For routine analyses, the Agilent 1290 Infinity II System brings the robustness that you need. Agilent 2D-LC Software for OpenLab CDS includes functionality like access control, audit trails, and system suitability tests, which are crucial in regulated environments. A dedicated protocol in the Agilent Compliance Engine (ACE) allows the qualification of 2D-LC instruments.

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Direct Analysis of In-Process Oligonucleotides Without Manual Purification

Already have a 1290 Infinity II LC or 1290 Infinity II Bio LC? Upgrading to a full 2D-LC system is easy and affordable.

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Achieve Ultimate Separation Power

Agilent InfinityLab 2D-LC Solutions

Achieve Ultimate
Separation Power

Agilent InfinityLab 2D-LC Solutions

Agilent ranks #1 in 2D-LC

Configure your 2D-LC