Biobank Best Practices for Nucleic Acid Samples

A hand in a blue glove holds an Eppendorf tube over a dewer with tweezers

Put Your Best Samples Forward

Enabling best practices for nucleic acid quality control

¹ Baker, M. 1,500 scientists lift the lid on reproducibility. Nature 533, 452–454 (2016)

²Checklists work to improve science, Nature 556, 273-274 (2018)

The research community relies on biobanks to deliver fit-for-purpose samples

Various international institutions and governing bodies (such as ISBER and ISO) have issued recommendations and guidelines for biobanks, including biospecimen DNA and RNA quality control.

These guidelines are meant to ensure reliable research results, as experimental reproducibility remains a significant challenge:

More than 70% of researchers have tried and failed to reproduce another scientist's experiments according to a Nature survey conducted in 2016¹.
In a later survey, 86% of respondents acknowledged that poor reproducibility is a problem (Nature, 2018)².

So how can you make sure your biobank is putting its best samples forward?

Objective sample quality assessment is the key to avoid wasting time and resources by using unfit samples in expensive applications such as NGS or mircoarray experiments.

Get objective results with quality metrics for sample QC

Objective sample quality metrics enable your group to decide if a sample meets your specifications.

Quality metrics are available for a variety of RNA and DNA samples used in workflows such as NGS. They provide you with unbiased integrity data for nucleic acid samples and are also applicable for unique types such as formalin-fixed paraffin-embedded (FFPE) and cell-free DNA (cfDNA) samples.

This video explains our objective quality metrics, helps you determine which metric to use for your sample, and shows you examples of different nucleic acid types and their resulting quality. Start the video!

Your new guide to best practices

A new white paper, "Quality Control of Nucleic Acids: Best Practices for Biobanks and Biorepositories", demonstrates how Agilent automated electrophoresis instruments are used in biobanks and how they can help you determine your best practices for handling, extracting, storing, and shipping of nucleic acids.

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For Research Use Only. Not for use in diagnostic procedures.

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Register below for the new white paper "Quality Control of Nucleic Acids: Best Practices for Biobanks and Biorepositories".

Put Your Best Samples Forward

The research community relies on biobanks to deliver fit-for-purpose samples

So how can you make sure your biobank is putting its best samples forward?

Get objective results with quality metrics for sample QC

Your new guide to best practices

Register here

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