Experience the power of DNA and methylation in one target enrichment workflow

Purpose-built to seek no fragment left behind, the Avida technology features high-efficiency capture through a novel probe technology that maintains the complexity of low-input samples while minimizing material loss and bias. High uniformity and percentage of on-target fragments is achieved for more efficient sequencing.

Thanks to the heightened efficiency of the Avida technology, steps like post-ligation elution or precapture PCR are unnecessary. The resulting single shift, sample-to-sequencer workflow enables one-hour hybridization and next-generation bisulfite conversion steps and less purification and QC steps, without compromising performance.

By allowing for consecutive captures from both DNA and Methyl targets from a single sample input, the Avida Duo workflow enables differentiated multiomic approaches without input sample splitting. Avida Methyl reagents deliver outstanding performance for input as low as 3 ng, leveraging the highly effective Avida core technology.

The Avida workflows are optimized for difficult sample types, including low-input cfDNA from liquid biopsies and formalin-fixed paraffin-embedded (FFPE) DNA from solid tumor biopsies, accommodating inputs as little as 1 ng (DNA) and 3 ng (Duo and Methyl). The technology was developed and verified using these challenging sample types to improve analytical sensitivity and gather more information from your precious samples.