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On Demand Webinar

Investigating Energy Metabolism Dysfunction in the Tox Space 

Dr. Jia Shenglan

Dr. Jia Shenglan

Research Fellow

Nanyang Environment & Water Research Institute (NEWRI)

In this webinar Dr. Jia Shenglan, research fellow from the Nanyang Environment & Water Research Institute (NEWRI) in Singapore, will discuss the investigation of toxicity effects and mechanisms underlying energy metabolism and dysregulation in the environmental toxicology space.

A novel cell analysis workflow featuring analysis of cellular bioenergetics using the Agilent XFe96 Seahorse and real-time oxidative stress assays using the xCELLigence RTCA eSight will be explored.

Key learning objectives

  • Learn about the effects of bisphenol analogs on energy metabolism
  • Discover how to characterize metabolome alterations and pathway disorders
  • Learn about a workflow that utilizes technology from Agilent Technologies (Seahorse, xCELLigence RTCA) and discover how this workflow is used in the environmental toxicology space to provide new insights
  • Explore data on induced alterations in mitochondrial health and membrane potential, ROS, proliferation of cells, and the effect on mitochondrial function and glycolysis
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