We know that your time is precious, so why not make the very best use of it? The application notes below describe ‘three front-end’ strategies to help you to get more analysis done each day. The selectivity and sensitivity of modern LC/MS instruments allows you to shorten traditional LC run times and to combine multiple analytes into a single short analysis, or alternatively to further shorten the chromatographic separation times by multiplexing the LC separation step using multiple LC systems with a single mass spectrometer. Advances in MS ionisation source design now enable large biomolecule applications to be achieved at standard flow rates using standard column technologies delivering a more robust and faster analysis compared to the conventional nanoflow approach.
Learn how method transfer from conventional nanoflow to a standard flow LC/MS platform considerably increases sample throughput whilst delivering a more robust and reproducible workflow than nanoflow LC/MS. Discover how the Agilent 1290 Infinity II LC coupled to the Agilent 6495 LC/TQ delivers routine measurement of PromarkerD protein markers.
This application note describes an analytical method for the sensitive and accurate simultaneous determination of four immunosuppressant drugs in whole blood using an Agilent Ultivo triple quadrupole LC/MS with an Agilent Jet Stream ionization source.
This Application Note demonstrates how the Agilent StreamSelect LC/MS system increases the throughput of traditional vitamin D. By mirroring an LC method on two HPLC systems and coordinating the use of a single triple quadrupole mass spectrometer, up to twice the throughput can be achieved without compromising performance